Orthobiologic Approaches for Bone and Cartilage Regeneration
Orthobiologics is a new field in orthopedics that combines an understanding of tissue biology, material sciences, and a new generation of growth factors. Orthobiologic approaches differ from traditional orthopedic therapies in that they use biomaterials that mimic the body's natural tissue environment. These new therapeutic options have the potential to reduce morbidity and hospital stays associated with current procedures, resulting in improved patient quality of life and reduced healthcare costs.
Orquest, Inc. (Mountain View, Calif.) is a pioneer in this new field. Orquest's two orthobiologic technologies in development are HealosTM and OssigelTM. Healos is an implantable bone graft material designed to eliminate an autograft--a painful and expensive secondary surgery routinely performed in spinal fusion. Healos provides a "scaffolding" for bone ingrowth and is completely replaced by new bone as part of the body's natural healing process. Ossigel is an injectable gel matrix designed to accelerate fracture healing. These technologies may be able to help the more than 200,000 patients who undergo spinal fusion procedures and 6 million people who suffer bone fractures in the United States each year.
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Unless otherwise indicated, all files are in text format.
Available Materials
Press Kit
- Corporate Backgrounder--Orquest, Inc.
- Fact Sheet--Orquest, Inc.
- Management Backgrounder--Orquest, Inc.
- Key Terms
News Releases & Media Advisories
- Orquest Completes $15
Million Mezzanine Financing
(12 August 1997) - Anika Therapeutics and Orquest Sign Manufacturing Agreement for OssigelTM (23 June 1997)
- Conference Highlights Revolutionary New Field of Orthobiologics for Bone, Cartilage, and Skin Regeneration: Orquest, Inc. Presentation Focuses on New Materials for Improving Spinal Fusion and Accelerating Fracture Healing (23 June 1997)
- Orquest and Spine-Tech Announce Alliance to Develop Minimally Invasive Spinal Fusion System (16 December 1996)
- Orquest Names New CEO (2 December 1996)
- Orquest Receives Grant to Investigate Polymer Matrices for Cartilage Regeneration (19 November 1996 )
- Orquest Presents First Animal Data on Ossigel® Fracture Healing Treatment: Study Shows Ossigel Accelerates Fracture Healing (9 September 1996)
- Orquest Announces First Clinical Trial of Healos® Bone Regeneration Implant: Study Focuses on Spinal Fusion in Degenerative Disc Disease (18 June 1996)
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